منابع مشابه
Anionic polymers. II. Inhibition of ribonuclease.
The hydrolysis of ribonucleic acid or a number of pyrimidine nucleotide 3’-phosphate esters as catalyzed by pancreatic ribonuclease is generally regarded as occurring in a biphasic fashion, the first phase involving formation of nucleoside-2’, 3’-cyclic phosphates, whereas the second involves hydrolysis of the cyclic intermediate to 3’-nucleoside phosphoric acids (1). Reports of inhibition of R...
متن کاملAnionic polymers. I. Inhibition of prostatic acid phosphatase.
In the course of synthesizing a number of aryl phosphate esters as substrates for prostatic acid phosphatase, polymeric phosphorylated products obtained by reaction of 4,4’-dihydroxybiphenyl with phosphorus oxychloride were found to be potent enzyme inhibitors. This report describes the preparation of these anionic polymers and some characteristics of their inhibition of prostatic acid phosphat...
متن کاملPolymers with complex architecture by living anionic polymerization.
1. Multifunctional Initiators. 3749 2. Multifunctional Linking Agents 3751 3. Use of Difunctional Monomers 3754 B. Star−Block Copolymers 3754 C. Functionalized Stars 3755 1. Functionalized Initiators 3755 2. Functionalized Terminating Agents 3756 D. Asymmetric Stars 3757 1. Molecular Weight Asymmetry 3757 2. Functional Group Asymmetry 3760 3. Topological Asymmetry 3761 E. Miktoarm Star Polymers...
متن کاملInfluence of Bacillus subtilis phoR on cell wall anionic polymers.
In Bacillus subtilis the Pho regulon is controlled by a sensor and regulator protein pair, PhoR and PhoP, that respond to phosphate concentrations. To facilitate studies of the Pho regulon, a strain with an altered PhoR protein was isolated by in vitro mutagenesis. The mutation in this strain (phoR12) leads to the production of a PhoR sensor kinase that, unlike the wild-type, is functionally ac...
متن کاملAnionic polymers of Bacillus subtilis cell wall modulate the folding rate of secreted proteins.
In order to characterize the dynamics of the interaction between the emergent membrane translocated exoprotein and the components of Bacillus subtilis cell wall, we examined the kinetics of the in vitro refolding of levansucrase and alpha-amylase, at pH 7 and 37 degrees C, in the presence of polyphosphates (polyP) of various chain lengths (2</=n</=65). These soluble anionic polymers are conside...
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ژورنال
عنوان ژورنال: Journal of Biological Chemistry
سال: 1958
ISSN: 0021-9258
DOI: 10.1016/s0021-9258(18)64733-7